Improving surgery for glaucoma
Professor Sir Peng T Khaw has a long and distinguished career in clinical ophthalmology and in ophthalmic research. His work aims to improve the long-term success of glaucoma operations, which has already benefited countless patients, including many children. His work on safer surgery and slowing down scarring after surgery has been adopted by eye surgeons around the world.
Improving eye drop treatments
It is now recognised that medicines for children should be properly evaluated in children rather than just being taken from the adult treatment range. As a result, companies which make eye drops for glaucoma often work with us to study safety and efficacy of these treatments in children. Around thirty of our young patients have taken part in international randomised controlled trials for the use of eye drops in children.
Some genes that can cause the faulty development at the front of the eye which leads to raised pressure in the eye are known but there may be many more. We therefore work with scientists at the UCL Institute of Child Health, led by Professor Jane Sowden, to identify more genes and to improve our understanding of the molecular pathways involved in the development of the eye.
Health-related quality of life
Two hundred families of children with glaucoma and other congenital eye defects have taken part in a survey addressing health-related quality of life. We have found that quality of life for children and families can suffer significantly due to these diagnoses. Results were found to be similar to those for families of children with serious, life-threatening illnesses.
Miss Papadopoulos leads the International Pilot Survey of Childhood Glaucoma (ISOCG), to which childhood glaucoma specialists worldwide have contributed. The aim of the study is to find out current treatment trends and outcomes for childhood glaucoma.